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MOTS-C

4.8 (230 reviews)
CAS 1627580-64-6 MW 2174.5 Da ≥ 99 % HPLC

A peptide hidden inside your mitochondrial DNA — not your nuclear DNA. MOTS-C only got discovered in 2015 and is one of the only "mitochondrial-derived" peptides known to humans.

Who it's for: Researchers studying mitochondrial-derived peptides and metabolic aging.

4.80 (230 customer reviews)
Released · In stock at the U.S. facility

−44%Save $40.01

CAS 1627580-64-6MW 2174.5 Da≥ 99 % HPLC

A peptide hidden inside your mitochondrial DNA — not your nuclear DNA. MOTS-C only got discovered in 2015 and is one of the only "mitochondrial-derived" peptides known to humans.

Who it's for: Researchers studying mitochondrial-derived peptides and metabolic aging.

In stock·Ships Tomorrow·48-hour express delivery
Code EXTRA10 auto-applied at checkout from $44.99
You save $45.01 total (50% off retail)
Dose
SKU: MOTS-C Category:

What research shows

  • 🔋Mitochondrial-derived — one of few known MDPs
  • 🏃Exercise-mimetic effects — in animal studies
  • 📅Discovered 2015 — newest class of peptides
Why Puripep: ≥99% HPLC verified · LAL endotoxin <10 EU/mg · third-party CoA per lot · ships in insulated cold-chain mailer · 48-hour express U.S. delivery
230 customer reviews 📦 ships in 1 business day ❄️ cold-chain insulated mailer 🇺🇸 synthesized in Carlsbad CA

Often paired with

The science behind it

MOTS-c is a 16-amino-acid peptide encoded within the 12S rRNA region of mitochondrial DNA. Activates AMPK, regulates glucose metabolism, and shows exercise-mimetic phenotypes in murine aging models published by Cohen lab.

Storage & reconstitution

Store lyophilized vial at −20 °C (long term) or 2–8 °C (short term, up to 30 days). Reconstitute with bacteriostatic water at the working concentration. After reconstitution, store at 2–8 °C and use within 28 days.

Quality & release standards

Each lot released only after passing: HPLC purity ≥99%, mass-spectrometry identity confirmation, and LAL endotoxin <10 EU/mg. Certificate of Analysis (CoA) issued per lot. U.S. synthesis (Carlsbad CA).

Research Use Only — MOTS-C is sold for in-vitro laboratory research and authorised professional use. Not for human or animal consumption. Not a medicinal product, supplement, food additive, or cosmetic. Customers represent they are a qualified researcher, laboratory, or institution.
  • ≥ 99 % HPLC purity
  • CoA on every vial
  • U.S. warehouse · flat $14.99

Available doses 10 mg | 40 mg

Reviews

4.8230 customer reviews
5189
436
35
20
10
Jasmine F.✓ Verified owner
June 24, 2026

sealed and no smudges. 10/10 easy

Donna N.✓ Verified owner
June 23, 2026

No leaking here and the seal was perfect. ill keep ordering.

Nicole H.✓ Verified owner
June 21, 2026

Vial arrived clean and sealed, no complaints.

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MOTS-C −44%Save $40.01
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